Faculty profile

James A. MacKenzie

Professor, Department Chair, Acting Advisement Coordinator


392A Shineman Center

Office hours

Meetings can be scheduled in the Biological Sciences office (315.312.2771 or 392 Shineman).

By appointment only

Jim MacKenzie


  • Environmental heavy metals and cardiovascular changes in children 
  • Effects of PCBs on fish and mussels
  • Intracellular protein trafficking to mitochondria

Specialty Areas:

  • molecular and cellular biology
  • physiology
  • human health and disease


* undergraduate research student, ** graduate research student

  1. Gump, B.B., B. Hruska, P.J. Parsons, C.D. Palmer, J.A. MacKenzie, K. Bendinskas, L. Brann (2020) Dietary Contributions to Increased Background Lead, Mercury, and Cadmium in 9-11 Year Old Children: Accounting for Racial Differences.  Environmental Research 185: 109308.
  2. Gump, B.B., M.J. Dykas, J.A. MacKenzie, A.K. Dumas, B. Hruska, C.K. Ewart, P.J. Parsons, C.D. Palmer, and K. Bendinskas (2017) Background lead and mercury exposures: Psychological and behavioral problems in children.  Environmental Research, 158:576-582. 
  3. Blodgett J.**, D. Walter*, J.A. MacKenzie,  B.B. Gump and K. Bendinskas. (2017) Both Hair Cortisol and Perceived Stress during Fall Exams Decrease after the Winter Break. Austin Biochem. 2(1): 1007.
  4. Gump, B.B., E. Gabrikova*, K. Bendinskas, A.K. Dumas, C.D. Palmer, P.J. Parsons, and J.A. MacKenzie (2014) Low-Level Mercury in Children: Associations with Sleep Duration and Cytokines TNF-α and IL-6. Environmental Research, 134:228-232.
  5. Miura, Y.*, E. Yeager*, J.A. MacKenzie, and K. Bendinskas (2014) Proteomic study of ribosomal proteins from E. coli, S. cerevisiae, B. Taurus, G. gallus, and O. tshawytscha and its application in a teaching laboratory setting. American Journal of Undergraduate Research, 12(1):27-37.
  6. Wang, F.*, C. Chmil*, F. Pierce*, K. Ganapathy, B. Gump, J.A. MacKenzie, Y. Metchref, and K. Bendinskas (2013) Immobilized Metal Affinity Chromatography and Human Serum Proteomics.  Chromatography B, Biological Applications, 934: 26-33.
  7. Gump, B.B.^, J.A. MacKenzie^, A.K. Dumas, C.D. Palmer, P.J. Parsons, Z.M. Segug, Y.S. Mechref, and K.G. Bendinskas (2012) Fish Consumption, Low-Level Mercury, Lipids, and Inflammatory Markers in Children. Environmental Research, 112: 204-211. ^Authors contributed equally to this paper.
  8. Bendinskas, K., P.S. Sattelberg*, D.J. Crossett*, A. Banyikwa**, D. Dempsey**, and J.A. MacKenzie (2011) Enzymatic Detection of Gamma-Hydroxybutyrate (GHB) Using Aldo-keto Reductase 7A2. Journal of Forensic Sciences, 56 (3): 783-787.
  9. Gump, B.B., J.A. MacKenzie, K.G. Bendinskas, R. Morgan, A.K. Dumas, C.D. Palmer and P.J. Parsons. (2011) Low-level Pb and Cardiovascular Responses to Acute Stress in Children: The Role of Cardiac Autonomic Regulation. Neurotoxicology and Teratology, 33(2):212-219.
  10. Birdsall, R.E.**, M.P. Kiley*, Z.M. Segu, C.D. Palmer, M. Madera, B.B. Gump, J.A. MacKenzie, P.J. Parsons, Y. Mechref, M.V. Novotny, and K.G. Bendinskas (2010) Effects of Lead and Mercury on the Blood Proteome of Children. Journal of Proteome Research, 9(9):4443-4453.
  11. MacKenzie, J.A., K.A. Roosa*, B.B. Gump, A.K. Dumas, and K.G. Bendinskas. (2010) Plasma Prekallikrein Levels are Positively Associated with Circulating Lipid Levels and the Metabolic Syndrome in Children. Applied Physiology, Nutrition, and Metabolism, 35(4):518-525.
  12. Nautiyal, M.**, A.J. Sweatt, J.A. MacKenzie, R.M. Payne, S. Szucs, R. Matalon, R. Wallin, and S.M. Hutson (2010) Neuronal localization of the mitochondrial protein NIPSNAP1 in rat nervous system. European Journal of Neuroscience, 32(4):560-569.
  13. Bosch, W.C., J.L. Hester, V.M. MacEntee, J.A. MacKenzie, T.M. Morey, J.T. Nichols, P.A. Pacitti, B.A. Shaffer, S.P. Weber, and R.R. Young, (2008) Beyond Lip-service: An Operational Definition of "Learning-centered College." Innovative Higher Education, 33(2):83-98.
  14. MacKenzie, J.A. and R.M. Payne (2007)  Mitochondrial Protein Import and Human Health and Disease.  Biochimica et Biophysica Acta, 1772(5):509-523.
  15. MacKenzie, J.A. and R.M. Payne (2006)  Preparation of Ribosomes Loaded with Truncated Nascent Proteins to Study Ribosome Binding to Mitochondria.  Mitochondrion, 6(2):67-75.
  16. MacKenzie, J.A. and R.M. Payne (2004)  Ribosomes Specifically Bind to Mammalian Mitochondria via Protease-sensitive Proteins on the Outer Membrane.  Journal of Biological Chemistry, 279(11):9803-9810.
  17. Del Gaizo, V.B., J.A. MacKenzie, and R.M. Payne (2003) Targeting Proteins to Mitochondria Using TAT.  Molecular Genetics and Metabolism, 80(1-2):170-180.


Ph.D., Molecular Medicine, Wake Forest University School of Medicine
M.S., Biology, Western Carolina University
B.S., Biology, SUNY Fredonia