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MacKenzie research lab

Students may inquire here if you are interested in any of the following research positions. See past and former lab members.

Active Projects

  1. Effect of environmental toxicants on the cardiovascular system of children
    • Various environmental toxicants have been shown to correlate with hypertension and cardiovascular reactivity children.
    • The goals of this project are
      • To determine the role of vasotone mediators and oxidant stress.
      • To characterize the plasma proteome of children with various toxicant levels.
    • In collaboration with Dr. Brooks Gump (Department of Health and Wellness, Syracuse University) and Dr. Kestas Bendinskas (Department of Chemistry, SUNY Oswego).
    • Currently funded by an NIH RO1 award (1R01ES023252-01A1; $1,809,000 for 2013-2016) and previously funded by an NIH Academic Research Enhancement Award Grant (R15) and the MERCK/AAAS Undergraduate Research Program
  2. Study of environmental toxicants in the environment
    • Organic toxicants (PCBs, dioxins) and inorganic toxicants (heavy metals) are found throughout the environment. 
    • The goals of this study are
      • To use high and low trophic species to assess the contamination of local waterways.
      • To use mussels as a model system to elicdate the toxicology of emerging organic toxicants.
    • In collaboration with James Pagano (Department of Chemstry, SUNY Oswego), Paul Tomascek (Atmospheric and Geological Sciences, SUNY Oswego)
  3. Protein Targeting to Mitochondria
    • Most all mitochondrial proteins are encoded in the nucleus and must be properly synthesized and imported to be fully functional.
    • The goal of this project is to identify the mechanisms involved in the import of mitochondrial proteins.