Molecular Biology & Biochemistry Research

Faculty and Publications

Kestas Bendinskas
picture of Kestas Bendinskas

Education

  • Post-doctoral fellow, John Hopkins University, 1996-1997
  • Ph.D., Bowling Green State University, 1996

Research Interests

Our group studies the biochemical effects of lead and other matals on cardiovascular proteins in children; develops date-rage kits for the drug GHB; creates new biochemistry teaching experiments; in general, uses proteomics and molecular biology tools to study the area of science where biology meets chemistry.

Publications

Birdsall, R.E., Kiley, M.P., Segu, Z.M., Palmer, C.D. Madera, M., Gump, B.B., MacKenzie, J.A. Parsons, P.J., Mechref, Y., Novotny, M.V., and Bendinskas, K.G.*, Effects of Lead and Mercury on the Blood Proteome of Children, 2010, Journal of Proteome Research, 9, 4443–4453.

Gump, B. B., MacKenzie, J. A., Bendinskas, K., Morgan, R., Dumas, A. K., Palmer, C. D., & Parsons, P. J., Low-level Pb and Cardiovascular Responses to Acute Stress in Children: The Role of Cardiac Autonomic Regulation, 2011, Neurotoxicology and Teratology,33, 212-219.

Gump, B. B., MacKenzie, J. A., Dumas, A. K., Palmer, C. D., Parsons, P. J., Segu, Z. M., Mechref, Y. S., and Bendinskas, K., Fish Consumption, Low-Level Mercury, Lipids, and Inflammatory Markers in Children, 2011, Environmental Research, XXX(X), XXX-XXX, manuscript in print.

Kestutis Bendinskas, Patricia Sattelberg, Daniel Crossett, Andrew Banyikwa, and Daniel Dempsey, James A. MacKenzie, Enzymatic Detection of Gamma-Hydroxybutyrate (GHB) Using Aldo-keto Reductase 7A2, 2011, Journal of Forensic Science, 56 (3), 783-787.

MacKenzie, J.A., Roosa, K.A., Gump, B.B., Dumas, A.K., and Bendinskas, K.G.., Plasma Prekallikrein Levels are Positively Associated with Circulating Lipid Levels and the Metabolic Syndrome in Children, Applied Physiology, Nutrition, and Metabolism, 35, 2010, 518-525.

Timothy Braun
picture of Timothy Braun

Education

  • Ph.D. Biology, University of Utah at Salt Lake City
  • B.S. Recombinant Gene Technology (Biology) and Chemistry, SUNY Ferdonia

Research Interests
Bacterial Motility and Bacterial Physiology with special interests in bioenergetics.

Publications
Braun, T.F., Khubbar, M., and McBride, M.J. (2005). Flavobacterium johnsoniae gliding motility genes identified by mariner mutagenesis. J. Bacteriol, 187:6943-6952.

Braun, T.F. and McBride, M.J. (2005) Flavobacterium johnsoniae GldJ is a lipoprotein that is required for gliding motility. J. Bacteriol, 187: 2628-2637.

Braun, T. F. and McBride, M. J. (2004) GldI is a lipoprotein that is required for Flavobacterium johnsoniae gliding motility and chitin utilization. J Bacteriol, 186: 2295-302.

Braun, T.F., Al-Mawsawi, L.Q., Kojima S. and Blair D.F. (2004) Arrangement of core membrane segments in the MotA/MotB proton-channel complex of Escherichia coli. Biochemistry, 43: 35-45.

Braun, T.F.,  McBride M.J. and Brust J.L. (2003) Flavobacterium johnsoniae GldH is a lipoprotein that is required for gliding motility and chitin utilization. J Bacteriol, 185: 6648-57.

Bruan, T.F., and Blair, D.F. (2001) Targeted disulfide cross-linking of the MotB protein of Escherichia coli: evidence for two H(+) channels in the stator complex. Biochemistry, 40: 13051-59.

 

Webe Kadmin
picture of Webe Kadima

Education

  • Visiting Scholar, Novo-Nordisk and the Royal Veternary and Agricultural University, Copenhagen, Denmark 1990
  • Postdoctural Fellow, University of California, Riverside, 1989
  • Ph.D. University of Alberta (Edmonton), 1987
  • M.Sc. University of Montreal, 1982

Research Interests
Effects of metal ion chemistry on the allosteric transitions of the insulin hexamer, Investigation of anti-diabetic medicinal plants from the Democtatic Replblic of Congo, Protein assocation in dilute and supersaturated solutions.

Publications
Kadima W., Olson H.B., Leunberger-Fisher M.R., Borchart, D., Kaarsholm N.C., and Dunn M.F. (2003) Structural signatures of the complex formed between 3-nitro-4-hydroxybenzoate and the Zn(II)-substituted R6 insulin hexamer. Protein Science, 12:1902-1913.

Kadima W. (1999) The Rold of metal ions in the T-to R-allosteric transition in the insulin hexamer, Biochemistry, 38:13444-13452.

Kadima W., Raharivelomanana P. and Bechtel B. (1997) The binding of cyclic adenosine 3', 5' monophosphate to the insulin hexamer, Protein and Peptide Letters, 4: 17-23.

Kadima W., Ogendal L., Bauer R., Kaarsholm N., Hansen J. and Irlind P. (1993) The influence of ionic strength and pH on the aggregation of zinc-free insulin studied by static and dynamic laser light scattering, Bioploymers, 33: 1643-1657.

 

Peter Rosenbaum
picture of Peter Rosenbaum

Education

  • Postdoctoral Fellow, Louisiana State University Medical Center, Specialized Center of Rewearch-Arteriosclerosis
  • Ph.D. Tulane University, 1981
  • M.S. Tulane University, 1976
  • B.S. Tulane University, 1974

Research Interests
Conservation, Genetics, Natural History, and Ecology Evolution. 

Publications
Rosenbaum, P.A., Robertson J.M. and Zamudio K. R. (2007) Unexpectedly low genetic variation among populations of the bog turtle (Glyptemys muhlenbergii), Conservation Genetics, 8: 331-3342.

Rosenbaum, P.A., Pagaon, J.J., Roberts, R.N., Sumner, G.M. and Williamson, L.V. (1999) Qualitative and quantitative assessment of maternal contaminant burden by analysis of snapping turtle eggs, Journal of Great Lakes Research, 25: 950-9-->

Fehmi Damkaci
picture of Fehmi Damkaci

Education

  • Post-doctural fellow, Boston College, 2004-2006
  • Ph.D., University of Maryland, College Park, 2004

Research Interests

(1) Total synthesis of heterocyclic natural products with medicinal and or structural importance, (2) Development of new synthetic organic reactions. Currently, my group has been involved in the discovery of new ligand for Ullman type aryl-aryl couplings. (3) Development of new experiments for undergraduate organic laboratory curriculum using microwave-assisted reactions. (4) Comparison of online vs. face-to-face course medium for a general chemistry course.