From: web-form@Oswego.EDU Sent: Thursday, April 10, 2008 1:13 AM To: ucc@oswego.edu Subject: Web Form: Course_Submission Department_Chair: Jeff Schneider Department_Chair_Email: schneidr@oswego.edu Additional_Contact: Martha Bruch (Chemistry Dept. curriculum committee chair) Additional_Contact_Email: bruch@oswego.edu Course_Number: CHE 344 Course_Type: New Course Course_Title: Physical Chemistry for Life Sciences Catalog_Description: This is a one semester course which covers all three areas of physical chemistry. It is intended as an alternative to CHE 341/342 for Biochemistry majors. Prerequisites: CHE 212, MAT 220 Sp_every Spring: Yes Semester_Hours: 4 Justification: This course is intended for Biochemistry majors as a one-semester alternative to CHE 341/342, which currently are required courses. It has less emphasis on mathematical problem solving and more emphasis on fundamental principles than CHE 341/342. In addition, this course has more emphasis on solution thermodynamics and less emphasis on gases and solids than CHE 341. Furthermore, this course includes more applications of thermodynamics and kinetics to problems in biochemistry than CHE 341/342. Course_Objectives: Upon completion of the course, students should be able to 1) Solve a variety of numerical problems in thermodynamics, kinetics, and quantum mechanics 2) Apply principles of thermodynamics to gain a better understanding of biochemical systems and processes 3) Describe molecular interactions that occur in solution, with emphasis on how these interactions effect biochemical processes, e.g. protein folding 4)Describe the fundamental concepts associated with quantum mechanics 5)Describe the characteristics of the energies and wavefunctions obtained by solving Schrodinger's equation for particle in a box, harmonic oscillator, and hydrogen atom model systems 6)Discuss advantages and disadvantages of methods for solving Schrodinger's equation for more complicated systems, e.g. many-electron atoms 7)Discuss information obtained from spectroscopic techniques, with emphasis on applications to biochemical systems 8)Describe the molecular basis for viscosity and diffusion in solutions 9)Derive rate laws associated with a given mechanism 10)Describe the physical significance of parameters used to characterize enzyme kinetics Course_Description: Course Outline: A. Thermodynamics • Fundamental Concepts • Heat, Work, Energy, Enthalpy • Thermochemistry • Entropy • Free Energy and Equilibrium • Phase Equilibria • Ideal and Real Solutions • Electrolyte Solutions B. Kinetics • Transport Properties • Elementary Chemical Kinetics • Enzyme Kinetics C. Quantum Mechanics and Spectroscopy • Classical versus Quantum Mechanics • The Schrodinger Equation • Particle in a Box • Harmonic Oscillator • Hydrogen Atom • Many-electron Atoms • Electronic Spectroscopy • Vibrational and Rotational Spectroscopy • NMR, X-Ray for Structure Determination Methods of Instruction: The method of instruction consists of four hours of lecture per week. Both readings from the text and end-of-chapter problems are assigned. Demonstrations and hands-on activities are included as appropriate. Course Requirements: Reading and homework assignments are made from a textbook selected by the instructor. Homework problems require the use of a scientific calculator and/or a computer. Means of Evaluation: There are two exams, a final exam, and quizzes. Homework assignments are collected and graded. Resources: No additional resources are needed beyond those already available in the Chemistry Department. Resources used are the same as currently used for CHE 341/342. Bibliography: 1. T. Engel, B. Drobny, and P. Reid Physical Chemistry for Life Sciences Prentice Hall, 2008. (Suggested Textbook) 2. T. Engel, P. Reid Physical Chemistry Prentice Hall, 2007. 3. R. Chang Physical Chemistry for the Biosciences University Sciences, 2005. 4. P. Atkins and J. dePaula Physical Chemistry, 7th Edition W.H. Freeman and Company, 2002. Other_Comments: This course is part of a proposed change in the chemistry requirements for Biochemistry majors approved by the chemistry department. Currently, it is difficult for students to fullfill the extensive requirements for a B.S. degree in Biochemistry within four years, resulting in students taking courses without the proper prerequisites and/or requiring more than 4 years to graduate. This course is intended to provide more flexibility in the Biochemistry program, making it easier for students to schedule courses in the proper sequence. The program change will reduce the required hours in phsical chemistry from 8 to 5, making it easier for students to graduate in 4 years. It is also hoped that this course will attract biology majors and will encourage interdisciplinary research projects for students. IP_Adress: 129.3.17.68