James A. MacKenzie
Title: Associate Professor and Department Chair
Education:
Ph.D. in Molecular Medicine, Wake Forest University School of Medicine, 2004
M.S. in Biology, Western Carolina University, 1999
B.S. in Biology, SUNY Fredonia, 1996
Areas of Specialty: Molecular and Cellular Biology, Physiology, Human Health and Disease
Research Interests:
Environmental Heavy Metals and Pediatric Health
Intracellular Protein Trafficking to Mitochondria
Obesity and the Metabolic Syndrome in Children
Recent Publications: (Denotes *Undergraduate or **Graduate Research Student)
Gump, B.B.^, J.A. MacKenzie^, A.K. Dumas, C.D. Palmer, P.J. Parsons, Z.M. Segug, Y.S. Mechref, and K.G. Bendinskas (2012) Fish Consumption, Low-Level Mercury, Lipids, and Inflammatory Markers in Children. Environmental Research, 112: 204-211 .
^ Authors contributed equally to this paper.
Bendinskas, K., P.S. Sattelberg*, D.J. Crossett*, A. Banyikwa**, D. Dempsey**, and J.A. MacKenzie (2011) Enzymatic Detection of Gamma-Hydroxybutyrate (GHB) Using Aldo-keto Reductase 7A2. Journal of Forensic Sciences, 56 (3): 783-787.
Gump, B.B., J.A. MacKenzie, K.G. Bendinskas, R. Morgan, A.K. Dumas, C.D. Palmer and P.J. Parsons. (2011) Low-level Pb and Cardiovascular Responses to Acute Stress in Children: The Role of Cardiac Autonomic Regulation. Neurotoxicology and Teratology, 33(2):212-219.
Birdsall, R.E.**, M.P. Kiley*, Z.M. Segu, C.D. Palmer, M. Madera, B.B. Gump, J.A. MacKenzie, P.J. Parsons, Y. Mechref, M.V. Novotny, and K.G. Bendinskas (2010) Effects of Lead and Mercury on the Blood Proteome of Children. Journal of Proteome Research, 9(9):4443-4453.
MacKenzie, J.A., K.A. Roosa*, B.B. Gump, A.K. Dumas**, and K.G. Bendinskas. (2010) Plasma Prekallikrein Levels are Positively Associated with Circulating Lipid Levels and the Metabolic Syndrome in Children. Applied Physiology, Nutrition, and Metabolism, 35(4):518-525.
Nautiyal, M., A.J. Sweatt, J.A. MacKenzie, R.M. Payne, S. Szucs, R. Matalon, R. Wallin, and S.M. Hutson (2010) Neuronal localization of the mitochondrial protein NIPSNAP1 in rat nervous system. European Journal of Neuroscience, 32(4):560-569.
Bosch, W.C., J.L. Hester, V.M. MacEntee, J.A. MacKenzie, T.M. Morey, J.T. Nichols, P.A. Pacitti, B.A. Shaffer, S.P. Weber, and R.R. Young, (2008) Beyond Lip-service: An Operational Definition of "Learning-centered College." Innovative Higher Education, 33(2):83-98.
MacKenzie, J.A. and R.M. Payne (2007) Mitochondrial Protein Import and Human Health and Disease. Biochimica et Biophysica Acta, 1772(5):509-523.
MacKenzie, J.A. and R.M. Payne (2006) Preparation of Ribosomes Loaded with Truncated Nascent Proteins to Study Ribosome Binding to Mitochondria. Mitochondrion, 6(2):67-75.
MacKenzie, J.A. and R.M. Payne (2004) Ribosomes Specifically Bind to Mammalian Mitochondria via Protease-sensitive Proteins on the Outer Membrane. Journal of Biological Chemistry, 279(11):9803-9810.
Del Gaizo, V.B., J.A. MacKenzie, and R.M. Payne (2003) Targeting Proteins to Mitochondria Using TAT. Molecular Genetics and Metabolism, 80(1-2):170-180.












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