Faculty profile
James A. MacKenzie
Professor, Department Chair
Contact
Website
Dr. MacKenzie's expanded websiteOffice hours
Meetings can be scheduled in the Biological Sciences office (315.312.2771 or 392 Shineman).
By appointment only
Research
- Environmental heavy metals and cardiovascular changes in children
- Effects of PCBs on fish and mussels
- Intracellular protein trafficking to mitochondria
Specialty Areas:
- molecular and cellular biology
- physiology
- human health and disease
Publications
* undergraduate research student, ** graduate research student
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Gump, B.B., K. Heffernan, L. Brann, D.T. Hill, C. Labrie-Cleary*, V. Jandev, J.A. MacKenzie, N.H. Atallah-Yunes, P.J. Parsons, C.D. Palmer, A.A. Roberts, and K. Bendinskas. (2023) Exposure to Arsenic and subclinical cardiovascular disease in 9–11-year-old children, Syracuse, NY. JAMA Network Open 6(6):e2321379
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Gump, B.B, B. Hruska, K. Heffernan, L.S. Brann, M. Voss, C. Labrie-Cleary*, H. Cheng*, J.A. MacKenzie, S. Woolf-King, S. Maisto, K. Bendinskas (2023) Race, cortisol, and subclinical cardiovascular disease in 9–11-year-old children. Health Psychology
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Hill, D.T., J. V. Jandev, M. Petroni, N. Atallah-Yunes, K. Bendinskas, L. Brann, K. Heffernan, D.A. Larsen, J.A. MacKenzie, C.D. Palmer, P.J. Parsons, B.B. Gump, and M.B. Collins (2023) Airborne levels of cadmium are correlated with urinary cadmium concentrations among young children living in the New York State city of Syracuse, USA. Environmental Research 223: 115450.
- Gump, B.B., K. Heffernan, K. Bendinskas, B. Hruska, J.A. MacKenzie, A. Park, L. Brann, N.H. Atallah-Yunes (2021) Poor Sleep Quality Associated With Greater Left Ventricular Mass in 9-11 year-old Children. Psychosomatic Medicine 83(3): 265
- Hill, D.T., M. Petroni, D.A. Larsen, K. Bendinskas, K. Heffernan, N. Atallah-Yunes, P.J. Parsons, C.D. Palmer, J.A. MacKenzie, M.B. Collins, B.B. Gump (2021) Linking metal (Pb, Hg, Cd) industrial air pollution risk to blood metal levels and cardiovascular functioning and structure among children in Syracuse, NY. Environmental Research 193:110557.
- Gump, B.B., B. Hruska, P.J. Parsons, C.D. Palmer, J.A. MacKenzie, K. Bendinskas, L. Brann (2020) Dietary Contributions to Increased Background Lead, Mercury, and Cadmium in 9-11 Year Old Children: Accounting for Racial Differences. Environmental Research 185: 109308.
- Gump, B.B., M.J. Dykas, J.A. MacKenzie, A.K. Dumas, B. Hruska, C.K. Ewart, P.J. Parsons, C.D. Palmer, and K. Bendinskas (2017) Background lead and mercury exposures: Psychological and behavioral problems in children. Environmental Research, 158:576-582.
- Blodgett J.**, D. Walter*, J.A. MacKenzie, B.B. Gump and K. Bendinskas. (2017) Both Hair Cortisol and Perceived Stress during Fall Exams Decrease after the Winter Break. Austin Biochem. 2(1): 1007.
- Gump, B.B., E. Gabrikova*, K. Bendinskas, A.K. Dumas, C.D. Palmer, P.J. Parsons, and J.A. MacKenzie (2014) Low-Level Mercury in Children: Associations with Sleep Duration and Cytokines TNF-α and IL-6. Environmental Research, 134:228-232.
- Miura, Y.*, E. Yeager*, J.A. MacKenzie, and K. Bendinskas (2014) Proteomic study of ribosomal proteins from E. coli, S. cerevisiae, B. Taurus, G. gallus, and O. tshawytscha and its application in a teaching laboratory setting. American Journal of Undergraduate Research, 12(1):27-37.
- Wang, F.*, C. Chmil*, F. Pierce*, K. Ganapathy, B. Gump, J.A. MacKenzie, Y. Metchref, and K. Bendinskas (2013) Immobilized Metal Affinity Chromatography and Human Serum Proteomics. Chromatography B, Biological Applications, 934: 26-33.
- Gump, B.B.^, J.A. MacKenzie^, A.K. Dumas, C.D. Palmer, P.J. Parsons, Z.M. Segug, Y.S. Mechref, and K.G. Bendinskas (2012) Fish Consumption, Low-Level Mercury, Lipids, and Inflammatory Markers in Children. Environmental Research, 112: 204-211. ^Authors contributed equally to this paper.
- Bendinskas, K., P.S. Sattelberg*, D.J. Crossett*, A. Banyikwa**, D. Dempsey**, and J.A. MacKenzie (2011) Enzymatic Detection of Gamma-Hydroxybutyrate (GHB) Using Aldo-keto Reductase 7A2. Journal of Forensic Sciences, 56 (3): 783-787.
- Gump, B.B., J.A. MacKenzie, K.G. Bendinskas, R. Morgan, A.K. Dumas, C.D. Palmer and P.J. Parsons. (2011) Low-level Pb and Cardiovascular Responses to Acute Stress in Children: The Role of Cardiac Autonomic Regulation. Neurotoxicology and Teratology, 33(2):212-219.
- Birdsall, R.E.**, M.P. Kiley*, Z.M. Segu, C.D. Palmer, M. Madera, B.B. Gump, J.A. MacKenzie, P.J. Parsons, Y. Mechref, M.V. Novotny, and K.G. Bendinskas (2010) Effects of Lead and Mercury on the Blood Proteome of Children. Journal of Proteome Research, 9(9):4443-4453.
- MacKenzie, J.A., K.A. Roosa*, B.B. Gump, A.K. Dumas, and K.G. Bendinskas. (2010) Plasma Prekallikrein Levels are Positively Associated with Circulating Lipid Levels and the Metabolic Syndrome in Children. Applied Physiology, Nutrition, and Metabolism, 35(4):518-525.
- Nautiyal, M.**, A.J. Sweatt, J.A. MacKenzie, R.M. Payne, S. Szucs, R. Matalon, R. Wallin, and S.M. Hutson (2010) Neuronal localization of the mitochondrial protein NIPSNAP1 in rat nervous system. European Journal of Neuroscience, 32(4):560-569.
- Bosch, W.C., J.L. Hester, V.M. MacEntee, J.A. MacKenzie, T.M. Morey, J.T. Nichols, P.A. Pacitti, B.A. Shaffer, S.P. Weber, and R.R. Young, (2008) Beyond Lip-service: An Operational Definition of "Learning-centered College." Innovative Higher Education, 33(2):83-98.
- MacKenzie, J.A. and R.M. Payne (2007) Mitochondrial Protein Import and Human Health and Disease. Biochimica et Biophysica Acta, 1772(5):509-523.
- MacKenzie, J.A. and R.M. Payne (2006) Preparation of Ribosomes Loaded with Truncated Nascent Proteins to Study Ribosome Binding to Mitochondria. Mitochondrion, 6(2):67-75.
- MacKenzie, J.A. and R.M. Payne (2004) Ribosomes Specifically Bind to Mammalian Mitochondria via Protease-sensitive Proteins on the Outer Membrane. Journal of Biological Chemistry, 279(11):9803-9810.
- Del Gaizo, V.B., J.A. MacKenzie, and R.M. Payne (2003) Targeting Proteins to Mitochondria Using TAT. Molecular Genetics and Metabolism, 80(1-2):170-180.
Education
Ph.D., Molecular Medicine, Wake Forest University School of Medicine
M.S., Biology, Western Carolina University
B.S., Biology, SUNY Fredonia