Faculty and Staff

James A. MacKenzie

Title: Associate Professor and Department Chair


Ph.D. in Molecular Medicine, Wake Forest University School of Medicine, 2004
M.S. in Biology, Western Carolina University, 1999
B.S. in Biology, SUNY Fredonia, 1996

Areas of Specialty: Molecular and Cellular Biology, Physiology, Human Health and Disease

Research Interests:
Environmental Heavy Metals and Pediatric Health
Environmental PCBs and Dioxins and Their Effect on Wildlife
Intracellular Protein Trafficking to Mitochondria

Recent Publications: (Denotes Oswego *Undergraduate or **Graduate Research Student)

Gump, B.B., E. Gabrikova*, K. Bendinskas, A.K. Dumas, C.D. Palmer, P.J. Parsons, and J.A. MacKenzie (2014) Low-Level Mercury in Children: Associations with Sleep Duration and Cytokines TNF-α and IL-6. Environmental Research, 134:228-232.

Miura, Y.*, E. Yeager*, J.A. MacKenzie, and K. Bendinskas (2014) Proteomic study of ribosomal proteins from E. coli, S. cerevisiae, B. Taurus, G. gallus, and O. tshawytscha and its application in a teaching laboratory setting. American Journal of Undergraduate Research, 12(1):27-37.

Wang, F.*, C. Chmil*, F. Pierce*, K. Ganapathy, B. Gump, J.A. MacKenzie, Y. Metchref, and K. Bendinskas (2013) Immobilized Metal Affinity Chromatography and Human Serum Proteomics.  Chromatography B, Biological Applications, 934: 26-33.

Gump, B.B.^, J.A. MacKenzie^, A.K. Dumas, C.D. Palmer, P.J. Parsons, Z.M. Segug, Y.S. Mechref, and K.G. Bendinskas (2012) Fish Consumption, Low-Level Mercury, Lipids, and Inflammatory Markers in Children. Environmental Research, 112: 204-211 .
      ^ Authors contributed equally to this paper.

Bendinskas, K., P.S. Sattelberg*, D.J. Crossett*, A. Banyikwa**, D. Dempsey**, and J.A. MacKenzie (2011) Enzymatic Detection of Gamma-Hydroxybutyrate (GHB) Using Aldo-keto Reductase 7A2. Journal of Forensic Sciences, 56 (3): 783-787.

Gump, B.B., J.A. MacKenzie, K.G. Bendinskas, R. Morgan, A.K. Dumas, C.D. Palmer and P.J. Parsons. (2011) Low-level Pb and Cardiovascular Responses to Acute Stress in Children: The Role of Cardiac Autonomic Regulation. Neurotoxicology and Teratology, 33(2):212-219.

Birdsall, R.E.**, M.P. Kiley*, Z.M. Segu, C.D. Palmer, M. Madera, B.B. Gump, J.A. MacKenzie, P.J. Parsons, Y. Mechref, M.V. Novotny, and K.G. Bendinskas (2010) Effects of Lead and Mercury on the Blood Proteome of Children. Journal of Proteome Research, 9(9):4443-4453.

MacKenzie, J.A., K.A. Roosa*, B.B. Gump, A.K. Dumas**, and K.G. Bendinskas. (2010) Plasma Prekallikrein Levels are Positively Associated with Circulating Lipid Levels and the Metabolic Syndrome in Children. Applied Physiology, Nutrition, and Metabolism, 35(4):518-525.

Nautiyal, M., A.J. Sweatt, J.A. MacKenzie, R.M. Payne, S. Szucs, R. Matalon, R. Wallin, and S.M. Hutson (2010) Neuronal localization of the mitochondrial protein NIPSNAP1 in rat nervous system. European Journal of Neuroscience, 32(4):560-569.

Bosch, W.C., J.L. Hester, V.M. MacEntee, J.A. MacKenzie, T.M. Morey, J.T. Nichols, P.A. Pacitti, B.A. Shaffer, S.P. Weber, and R.R. Young, (2008) Beyond Lip-service: An Operational Definition of "Learning-centered College." Innovative Higher Education, 33(2):83-98.

MacKenzie, J.A. and R.M. Payne (2007)  Mitochondrial Protein Import and Human Health and Disease.  Biochimica et Biophysica Acta, 1772(5):509-523.

MacKenzie, J.A. and R.M. Payne (2006)  Preparation of Ribosomes Loaded with Truncated Nascent Proteins to Study Ribosome Binding to Mitochondria.  Mitochondrion, 6(2):67-75.

MacKenzie, J.A. and R.M. Payne (2004)  Ribosomes Specifically Bind to Mammalian Mitochondria via Protease-sensitive Proteins on the Outer Membrane.  Journal of Biological Chemistry, 279(11):9803-9810.

Del Gaizo, V.B., J.A. MacKenzie, and R.M. Payne (2003) Targeting Proteins to Mitochondria Using TAT.  Molecular Genetics and Metabolism, 80(1-2):170-180.