Poongodi Geetha-Loganathan

Title: Assistant Professor

Education:
Ph.D. Developmental Biology, 2006, University of Freiburg, Germany
M.Sc. Life Sciences, 2000, Bharathidasan University, India

Area(s) of Specialty: Developmental Biology; Cellular and Molecular Embryology; Gene Expression and Morphogenesis; Organismic and Evolutionary Biology

Research Interests: The research of my group focuses on cellular and molecular mechanisms that underlie embryonic development. Using chick and turtle embryos we study the genetic basis by which form and structure are regulated during vertebrate development. We are particularly interested in the signals that control cell fate decisions. 

Recent Publications:
1.     Geetha-Loganathan P, Nimmagadda S, Fu K, Richman JM. (2014). Avian Facial Morphogenesis is Regulated by JNK/PCP Wingless-Related (WNT) Signaling. J. Biol. Chem (in press)

2.     Hosseini-Farahabadi S, Geetha-Loganathan P, Nimmagadda S, Fu K, Richman JM. (2013). Dual functions for WNT5A during cartilage development and in disease.  Matrix Biology 32(5): 252-64

3.       Geetha-Loganathan P, Nimmagadda N, Hafez I, Fu K, Cullis, Richman JM. (2011). Development of high-concentration lipoplex for in vivo gene function studies in vertebrate embryos. Dev Dyn 240(9): 2108-2119.

4.       Geetha-Loganathan P, Nimmagadda S, Christ B, Huang R, Scaal M. (2010). Ectodermal Wnt6 is an early negative regulator of limb chondrogenesis in the chicken embryo. BMC Dev Biol 10:32.

5.       Buchtová M, Kuo WP, Nimmagadda S, Benson SL, Geetha-Loganathan P, Logan C, Au-Yeung T, Chiang E, Fu K, Richman JM. (2009). Whole genome microarray analysis of chicken embryo facial prominences. Dev Dyn 239(2): 574-591.

6.       Geetha-Loganathan P, Nimmagadda S, Fu K, Whiting CJ, Richman JM. (2009). Expression of WNT signalling pathway genes during chicken craniofacial development. Dev Dyn 238(5): 1150-1165.

7.       Szabo-Rogers HL, Geetha-Loganathan P, Whiting CJ, Nimmagadda S, Fu KK, Richman JM (2009). The olfactory placode is necessary and sufficient to pattern the lateral nasal skeleton Development 136(2): 219-29.

8.       Szabo-Rogers HL, Geetha-Loganathan P, Nimmagadda S, Fu KK, Richman JM (2008). FGF signals from the nasal pit are necessary for normal facial morphogenesis. Dev Biol. 318(2): 289-302.

9.       Geetha-Loganathan P, Nimmagadda S, Scaal M, Huang R, Christ B. (2008). Wnt signaling in somite development. Ann Anat (invited review). 190(3): 208-222.

10.    Geetha-Loganathan P, Nimmagadda S, Scaal M. (2008). Wnt signaling in Limb             Organogenesis. Organogenesis (invited review). 4(2): 109-115.

11.    Nimmagadda S, Geetha-Loganathan P, Pröls F, Scaal M, Christ B, Huang R. (2007). Expression and Regulation of Dll4 during chick embryogenesis. Histochem Cell Biol 128(2): 147-152.

12.    Nimmagadda S, Geetha-Loganathan P, Scaal M, Christ B, Huang R. (2007). FGFs, Wnts and BMPs mediate induction of VEGFR-2 (Quek1) expression during avian somite development Dev Biol 305(2): 421-429.

13.    Nimmagadda S, Geetha-Loganathan P, Pröls F, Scaal M, Christ B, Huang R. (2007). Expression pattern of Vasohibin during chick development Dev Dyn 236(5): 1358-1362.

14.    Geetha-Loganathan P, Nimmagadda S, Huang R, Scaal M, Christ B. (2006). Expression pattern of BMPs during chick limb development. Anat Embryol (Berl) 211(1): 87-93.

15.    Geetha-Loganathan P, Nimmagadda S, Huang R, Christ B, Scaal M. (2006). Regulation of ectodermal Wnt6 expression by the neural tube is transduced by dermomyotomal Wnt11: a mechanism of dermomyotomal lip sustainment. Development 133(15): 2897-904.

16.    Geetha-Loganathan P, Nimmagadda S, Huang R, Scaal M, Christ B. (2006). Role of Wnt-6 in limb myogenesis. Anat Embryol (Berl) 211(3): 183-8.

17.    Geetha-Loganathan P, Nimmagadda S, Prols F, Patel K, Scaal M, Huang R, Christ B. (2005). Ectodermal Wnt-6 promotes Myf5-dependent avian limb myogenesis. Dev Biol 288(1): 221-33.

18.    Wang B, He L, Ehehalt F, Geetha-Loganathan P, Nimmagadda S, Christ B, Scaal M, Huang R. (2005). The formation of the avian scapula blade takes place in the hypaxial domain of the somites and requires somatopleure-derived BMP signals. Dev Biol 287(1): 11-8.

19.    Nimmagadda S, Geetha Loganathan P, Huang R, Scaal M, Schmidt C, Christ B. (2005). BMP4 and noggin control embryonic blood vessel formation by antagonistic regulation of VEGFR-2 (Quek1) expression. Dev Biol 280(1): 100-10.

20.    Loganathan PG, Nimmagadda S, Huang R, Scaal M, Christ B. (2005). Comparative analysis of the expression patterns of Wnts during chick limb development. Histochem Cell Biol 123(2): 195-201.

21.    Nimmagadda S, Loganathan PG, Wilting J, Christ B, Huang R. (2004). Expression pattern of VEGFR-2 (Quek1) during quail development. Anat Embryol (Berl) 208(3): 219-24.

22.    Inoue S, Poongodi GL, Suresh N, Chang T, Inoue Y. (2006). Identification and partial characterization of soluble and membrane-bound KDN(deaminoneuraminic acid)-glycoproteins in human ovarian teratocarcinoma PA-1, and enhanced expression of free and bound KDN in cells cultured in mannose-rich media. Glycoconj J 23(5-6): 401-410.

23.    Inoue S, Poongodi GL, Suresh N, Jennings HJ, Inoue Y. (2003). Discovery of an alpha 2, 9-PolyNeu5Ac glycoprotein in C-1300 murine neuroblastoma (clone NB41A3). J Biol Chem 278(10): 8541-8546.

24.    Poongodi GL, Suresh N, Gopinath SC, Chang T, Inoue S, Inoue Y. (2002). Dynamic change of neural cell adhesion molecule polysialylation on human neuroblastoma (IMR-32) and rat pheochromocytoma (PC-12) cells during growth and differentiation. J Biol Chem 277(31): 28200-28211.